For total protein intake (which had a significant interaction with sex), there was no significant association with blood pressure in women, nor in men after adjusting for dietary confounders. For animal protein intake, significant positive blood pressure differences did not persist after adjusting for height and weight. After adjusting for confounders, blood pressure differences associated with higher vegetable protein intake of 2.8% kilocalories were -2.14 mm Hg systolic and -1.35 mm Hg diastolic (P<.001 for both) after further adjustment for height and weight, these differences were -1.11 mm Hg systolic (P<.01) and -0.71 mm Hg diastolic (P<.05). There was a significant inverse relationship between vegetable protein intake and blood pressure. Two 24-hour urine samples were obtained per person. Information on dietary supplements was noted. Dietary intake based on 24-hour dietary recalls was recorded 4 times. Systolic and diastolic blood pressure was measured 8 times at 4 visits. Findings from epidemiological studies suggest an inverse relationship between individuals' protein intake and their blood pressure.Ĭross-sectional epidemiological study of 4680 persons, aged 40 to 59 years, from 4 countries.
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